Samuel Eto’o has been banned from 15 matches by the Cameroonian Football Federation (Fecafoot) for his participation in a players’ strike.
The strike was as result of a row over bonuses after a tournament in Morocco in November and led to the cancellation of a friendly match against Algeria.
Eto’o has been given 10 days to petition the ban.
Vice-captain Enoh Eyong received a two-match ban, while Tottenham’s Benoit Assou-Ekotto was given a fine of $1,980 (£1,276).
Since Cameroon did not qualify for the 2012 Africa Cup of Nations finals, the only actions Eto’o will be missing are the Indomitable Lions’ opening in qualifiers for the 2013 Africa Cup of Nations and the World Cup of 2014.
Cameroon begins their bid to reach the 2013 Nations Cup finals against Guinea Bissau on 29 February, with the return leg of the tie on 17 June.
They start their quest to reach the 2014 World Cup in Brazil with a match on 1 June against DR Congo.
Eto’o is the most decorated player in African history having won the European Champions League three times during his time at Barcelona and Inter Milan.
He has been awarded the title of African Footballer of the Year four times and has won an Olympic gold medal with Cameroon in 2000 and the Africa Cup of Nations in 2000 and 2002.
In August 2011, Eto’o moved to Russian club Anzhi Makhachkala and became one of the world’s best paid sportsmen.